ASCC3-SYNE1 Fusion FISH Probe
The ASCC3-SYNE1 Fusion FISH Probe is used to confirm a fusion of the ASCC3 and SYNE1 genes. The fusion of the ASCC3 and SYNE1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ASCC3-SYNE1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-RERE | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-REOR | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-REGO | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-REGR | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-REAQ | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-ORRE | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-OROR | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-ORGO | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-GORE | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-GOOR | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-GOGO | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-GOGR | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-GRRE | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-GROR | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-GRGO | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-GRGR | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-AQRE | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-AQOR | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-AQGO | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-AQGR | 20 (40 μL) | 200 μL |
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| ASCC3-SYNE1-20-AQAQ | 20 (40 μL) | 200 μL |
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ASCC3 Gene Summary
This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: Activating Signal Cointegrator 1 Complex Subunit 3
Chromosome: CHR6: 100956607 -101329224
Locus: 6q16.3
SYNE1 Gene Summary
This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Spectrin Repeat Containing Nuclear Envelope Protein 1
Chromosome: CHR6: 152442818 -152958534
Locus: 6q25.2
Gene Diseases
The ASCC3 SYNE1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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