ASAP1-LRRCC1 Fusion FISH Probe
The ASAP1-LRRCC1 Fusion FISH Probe is used to confirm a fusion of the ASAP1 and LRRCC1 genes. The fusion of the ASAP1 and LRRCC1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ASAP1-LRRCC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-RERE | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-REOR | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-REGO | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-REGR | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-REAQ | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-ORRE | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-OROR | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-ORGO | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-GORE | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-GOOR | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-GOGO | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-GOGR | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-GRRE | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-GROR | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-GRGO | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-GRGR | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-AQRE | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-AQOR | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-AQGO | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-AQGR | 20 (40 μL) | 200 μL |
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| ASAP1-LRRCC1-20-AQAQ | 20 (40 μL) | 200 μL |
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ASAP1 Gene Summary
This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: ArfGAP With SH3 Domain, Ankyrin Repeat And PH Domain 1
Chromosome: CHR8: 131064352 -131414217
Locus: 8q24.21-q24.22
LRRCC1 Gene Summary
This gene encodes a centrosomal protein that maintains the structural integrity of the centrosome and plays a key role in mitotic spindle formation. The encoded protein contains an N-terminal leucine-rich repeat domain and a C-terminal coiled-coil domain. It associates with the centrosome throughout the cell cycle and accumulates on the mitotic centrosome. [provided by RefSeq, Mar 2017]
Gene Name: Leucine Rich Repeat And Coiled-coil Centrosomal Protein 1
Chromosome: CHR8: 86019322 -86058314
Locus: 8q21.2
Gene Diseases
The ASAP1 LRRCC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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