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AS3MT-SUFU Fusion FISH Probe

The AS3MT-SUFU Fusion FISH Probe is used to confirm a fusion of the AS3MT and SUFU genes. The fusion of the AS3MT and SUFU genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AS3MT-SUFU-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AS3MT-SUFU-20-RERE 20 (40 μL) 200 μL
AS3MT-SUFU-20-REOR 20 (40 μL) 200 μL
AS3MT-SUFU-20-REGO 20 (40 μL) 200 μL
AS3MT-SUFU-20-REGR 20 (40 μL) 200 μL
AS3MT-SUFU-20-REAQ 20 (40 μL) 200 μL
AS3MT-SUFU-20-ORRE 20 (40 μL) 200 μL
AS3MT-SUFU-20-OROR 20 (40 μL) 200 μL
AS3MT-SUFU-20-ORGO 20 (40 μL) 200 μL
AS3MT-SUFU-20-ORAQ 20 (40 μL) 200 μL
AS3MT-SUFU-20-GORE 20 (40 μL) 200 μL
AS3MT-SUFU-20-GOOR 20 (40 μL) 200 μL
AS3MT-SUFU-20-GOGO 20 (40 μL) 200 μL
AS3MT-SUFU-20-GOGR 20 (40 μL) 200 μL
AS3MT-SUFU-20-GOAQ 20 (40 μL) 200 μL
AS3MT-SUFU-20-GRRE 20 (40 μL) 200 μL
AS3MT-SUFU-20-GROR 20 (40 μL) 200 μL
AS3MT-SUFU-20-GRGO 20 (40 μL) 200 μL
AS3MT-SUFU-20-GRGR 20 (40 μL) 200 μL
AS3MT-SUFU-20-GRAQ 20 (40 μL) 200 μL
AS3MT-SUFU-20-AQRE 20 (40 μL) 200 μL
AS3MT-SUFU-20-AQOR 20 (40 μL) 200 μL
AS3MT-SUFU-20-AQGO 20 (40 μL) 200 μL
AS3MT-SUFU-20-AQGR 20 (40 μL) 200 μL
AS3MT-SUFU-20-AQAQ 20 (40 μL) 200 μL

SUFU Gene Summary

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Gene Name: SUFU Negative Regulator Of Hedgehog Signaling

Chromosome: CHR10: 104263718 -104393214

Locus: 10q24.32

AS3MT Gene Summary

AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]).[supplied by OMIM, Mar 2008]

Gene Name: Arsenite Methyltransferase

Chromosome: CHR10: 104629209 -104661655

Locus: 10q24.32

Gene Diseases

The AS3MT SUFU Fusion has been associated with the following diseases:

Disease Name
Adrenocortical Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.