ARV1-CAPN9 Fusion FISH Probe
The ARV1-CAPN9 Fusion FISH Probe is used to confirm a fusion of the ARV1 and CAPN9 genes. The fusion of the ARV1 and CAPN9 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARV1-CAPN9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-RERE | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-REOR | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-REGO | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-REGR | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-REAQ | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-ORRE | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-OROR | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-ORGO | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-GORE | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-GOOR | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-GOGO | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-GOGR | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-GRRE | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-GROR | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-GRGO | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-GRGR | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-AQRE | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-AQOR | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-AQGO | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-AQGR | 20 (40 μL) | 200 μL |
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| ARV1-CAPN9-20-AQAQ | 20 (40 μL) | 200 μL |
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CAPN9 Gene Summary
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Calpain 9
Chromosome: CHR1: 230883160 -230937749
Locus: 1q42.2
ARV1 Gene Summary
this gene encodes a transmembrane protein that contains a conserved zinc ribbon motif at the N- terminus. A similar protein in mouse is thought to function in fatty acid homeostasis. Mutations in this gene are associated with early infantile epileptic encephalopathy 38. [provided by RefSeq, Nov 2016]
Gene Name: ARV1 Homolog, Fatty Acid Homeostasis Modulator
Chromosome: CHR1: 231114822 -231136479
Locus: 1q42.2
Gene Diseases
The ARV1 CAPN9 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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