ARRB1-RASSF3 Fusion FISH Probe
The ARRB1-RASSF3 Fusion FISH Probe is used to confirm a fusion of the ARRB1 and RASSF3 genes. The fusion of the ARRB1 and RASSF3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARRB1-RASSF3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-RERE | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-REOR | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-REGO | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-REGR | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-REAQ | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-ORRE | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-OROR | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-ORGO | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-GORE | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-GOOR | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-GOGO | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-GOGR | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-GRRE | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-GROR | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-GRGO | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-GRGR | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-AQRE | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-AQOR | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-AQGO | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-AQGR | 20 (40 μL) | 200 μL |
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| ARRB1-RASSF3-20-AQAQ | 20 (40 μL) | 200 μL |
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ARRB1 Gene Summary
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]
Gene Name: Arrestin Beta 1
Chromosome: CHR11: 74971165 -75062875
Locus: 11q13.4
RASSF3 Gene Summary
The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 2003]
Gene Name: Ras Association Domain Family Member 3
Chromosome: CHR12: 65004292 -65091347
Locus: 12q14.2
Gene Diseases
The ARRB1 RASSF3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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