ARPC1B-TRRAP Fusion FISH Probe
The ARPC1B-TRRAP Fusion FISH Probe is used to confirm a fusion of the ARPC1B and TRRAP genes. The fusion of the ARPC1B and TRRAP genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARPC1B-TRRAP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-RERE | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-REOR | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-REGO | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-REGR | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-REAQ | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-ORRE | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-OROR | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-ORGO | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-GORE | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-GOOR | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-GOGO | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-GOGR | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-GRRE | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-GROR | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-GRGO | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-GRGR | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-AQRE | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-AQOR | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-AQGO | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-AQGR | 20 (40 μL) | 200 μL |
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| ARPC1B-TRRAP-20-AQAQ | 20 (40 μL) | 200 μL |
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TRRAP Gene Summary
This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Transformation/transcription Domain Associated Protein
Chromosome: CHR7: 98476112 -98610864
Locus: 7q22.1
ARPC1B Gene Summary
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq, Mar 2011]
Gene Name: Actin Related Protein 2/3 Complex Subunit 1B
Chromosome: CHR7: 98972297 -98992404
Locus: 7q22.1
Gene Diseases
The ARPC1B TRRAP Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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