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ARNT2-MS4A3 Fusion FISH Probe

The ARNT2-MS4A3 Fusion FISH Probe is used to confirm a fusion of the ARNT2 and MS4A3 genes. The fusion of the ARNT2 and MS4A3 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ARNT2-MS4A3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ARNT2-MS4A3-20-RERE 20 (40 μL) 200 μL
ARNT2-MS4A3-20-REOR 20 (40 μL) 200 μL
ARNT2-MS4A3-20-REGO 20 (40 μL) 200 μL
ARNT2-MS4A3-20-REGR 20 (40 μL) 200 μL
ARNT2-MS4A3-20-REAQ 20 (40 μL) 200 μL
ARNT2-MS4A3-20-ORRE 20 (40 μL) 200 μL
ARNT2-MS4A3-20-OROR 20 (40 μL) 200 μL
ARNT2-MS4A3-20-ORGO 20 (40 μL) 200 μL
ARNT2-MS4A3-20-ORAQ 20 (40 μL) 200 μL
ARNT2-MS4A3-20-GORE 20 (40 μL) 200 μL
ARNT2-MS4A3-20-GOOR 20 (40 μL) 200 μL
ARNT2-MS4A3-20-GOGO 20 (40 μL) 200 μL
ARNT2-MS4A3-20-GOGR 20 (40 μL) 200 μL
ARNT2-MS4A3-20-GOAQ 20 (40 μL) 200 μL
ARNT2-MS4A3-20-GRRE 20 (40 μL) 200 μL
ARNT2-MS4A3-20-GROR 20 (40 μL) 200 μL
ARNT2-MS4A3-20-GRGO 20 (40 μL) 200 μL
ARNT2-MS4A3-20-GRGR 20 (40 μL) 200 μL
ARNT2-MS4A3-20-GRAQ 20 (40 μL) 200 μL
ARNT2-MS4A3-20-AQRE 20 (40 μL) 200 μL
ARNT2-MS4A3-20-AQOR 20 (40 μL) 200 μL
ARNT2-MS4A3-20-AQGO 20 (40 μL) 200 μL
ARNT2-MS4A3-20-AQGR 20 (40 μL) 200 μL
ARNT2-MS4A3-20-AQAQ 20 (40 μL) 200 μL

MS4A3 Gene Summary

This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]

Gene Name: Membrane Spanning 4-domains A3

Chromosome: CHR11: 59824100 -59838588

Locus: 11q12.1

ARNT2 Gene Summary

This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Dec 2013]

Gene Name: Aryl Hydrocarbon Receptor Nuclear Translocator 2

Chromosome: CHR15: 80696691 -80890277

Locus: 15q25.1

Gene Diseases

The ARNT2 MS4A3 Fusion has been associated with the following diseases:

Disease Name
Kidney Renal Clear Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.