ARL8B-ITPR1 Fusion FISH Probe
The ARL8B-ITPR1 Fusion FISH Probe is used to confirm a fusion of the ARL8B and ITPR1 genes. The fusion of the ARL8B and ITPR1 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma, Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma, and Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARL8B-ITPR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-RERE | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-REOR | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-REGO | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-REGR | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-REAQ | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-ORRE | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-OROR | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-ORGO | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-GORE | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-GOOR | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-GOGO | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-GOGR | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-GRRE | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-GROR | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-GRGO | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-GRGR | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-AQRE | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-AQOR | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-AQGO | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-AQGR | 20 (40 μL) | 200 μL |
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| ARL8B-ITPR1-20-AQAQ | 20 (40 μL) | 200 μL |
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ITPR1 Gene Summary
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]
Gene Name: Inositol 1,4,5-trisphosphate Receptor Type 1
Chromosome: CHR3: 4535031 -4889524
Locus: 3p26.1
ARL8B Gene Summary
The ADP Ribosylation Factor Like GTPase 8B (ARL8B) gene is located on chr3 :5163929-5222601 at 3p26.1.
Gene Name: ADP Ribosylation Factor Like GTPase 8B
Chromosome: CHR3: 5163929 -5222601
Locus: 3p26.1
Gene Diseases
The ARL8B ITPR1 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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