ARIH2-SLC25A20 Fusion FISH Probe
The ARIH2-SLC25A20 Fusion FISH Probe is used to confirm a fusion of the ARIH2 and SLC25A20 genes. The fusion of the ARIH2 and SLC25A20 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARIH2-SLC25A20-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-RERE | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-REOR | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-REGO | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-REGR | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-REAQ | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-ORRE | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-OROR | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-ORGO | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-GORE | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-GOOR | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-GOGO | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-GOGR | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-GRRE | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-GROR | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-GRGO | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-GRGR | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-AQRE | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-AQOR | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-AQGO | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-AQGR | 20 (40 μL) | 200 μL |
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| ARIH2-SLC25A20-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC25A20 Gene Summary
This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. [provided by RefSeq, Jul 2008]
Gene Name: Solute Carrier Family 25 Member 20
Chromosome: CHR3: 48894355 -48936426
Locus: 3p21.31
ARIH2 Gene Summary
The protein encoded by this gene is an E3 ubiquitin-protein ligase that polyubiquitinates some proteins, tagging them for degradation. The encoded protein upregulates p53 in some cancer cells and may inhibit myelopoiesis. Several transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been determined yet. [provided by RefSeq, Nov 2015]
Gene Name: Ariadne RBR E3 Ubiquitin Protein Ligase 2
Chromosome: CHR3: 48956280 -49022971
Locus: 3p21.31
Gene Diseases
The ARIH2 SLC25A20 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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