ARID1B-SYNE1 Fusion FISH Probe
The ARID1B-SYNE1 Fusion FISH Probe is used to confirm a fusion of the ARID1B and SYNE1 genes. The fusion of the ARID1B and SYNE1 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARID1B-SYNE1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-RERE | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-REOR | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-REGO | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-REGR | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-REAQ | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-ORRE | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-OROR | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-ORGO | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-GORE | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-GOOR | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-GOGO | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-GOGR | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-GRRE | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-GROR | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-GRGO | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-GRGR | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-AQRE | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-AQOR | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-AQGO | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-AQGR | 20 (40 μL) | 200 μL |
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| ARID1B-SYNE1-20-AQAQ | 20 (40 μL) | 200 μL |
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SYNE1 Gene Summary
This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Spectrin Repeat Containing Nuclear Envelope Protein 1
Chromosome: CHR6: 152442818 -152958534
Locus: 6q25.2
ARID1B Gene Summary
This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Gene Name: AT-rich Interaction Domain 1B
Chromosome: CHR6: 157099063 -157531913
Locus: 6q25.3
Gene Diseases
The ARID1B SYNE1 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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