ARID1B-SNX9 Fusion FISH Probe
The ARID1B-SNX9 Fusion FISH Probe is used to confirm a fusion of the ARID1B and SNX9 genes. The fusion of the ARID1B and SNX9 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARID1B-SNX9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-RERE | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-REOR | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-REGO | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-REGR | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-REAQ | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-ORRE | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-OROR | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-ORGO | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-GORE | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-GOOR | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-GOGO | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-GOGR | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-GRRE | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-GROR | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-GRGO | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-GRGR | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-AQRE | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-AQOR | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-AQGO | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-AQGR | 20 (40 μL) | 200 μL |
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| ARID1B-SNX9-20-AQAQ | 20 (40 μL) | 200 μL |
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SNX9 Gene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein does not contain a coiled coil region, like some family members, but does contain a SRC homology domain near its N-terminus. The encoded protein is reported to have a variety of interaction partners, including of adaptor protein 2 , dynamin, tyrosine kinase non-receptor 2, Wiskott-Aldrich syndrome-like, and ARP3 actin-related protein 3. The encoded protein is implicated in several stages of intracellular trafficking, including endocytosis, macropinocytosis, and F-actin nucleation. [provided by RefSeq, Jul 2013]
Gene Name: Sorting Nexin 9
Chromosome: CHR6: 158244293 -158366109
Locus: 6q25.3
ARID1B Gene Summary
This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Gene Name: AT-rich Interaction Domain 1B
Chromosome: CHR6: 157099063 -157531913
Locus: 6q25.3
Gene Diseases
The ARID1B SNX9 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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