ARID1B-SMOC2 Fusion FISH Probe
The ARID1B-SMOC2 Fusion FISH Probe is used to confirm a fusion of the ARID1B and SMOC2 genes. The fusion of the ARID1B and SMOC2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARID1B-SMOC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ARID1B-SMOC2-20-AQAQ | 20 (40 μL) | 200 μL |
|
ARID1B Gene Summary
This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Gene Name: AT-rich Interaction Domain 1B
Chromosome: CHR6: 157099063 -157531913
Locus: 6q25.3
SMOC2 Gene Summary
This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: SPARC Related Modular Calcium Binding 2
Chromosome: CHR6: 168841830 -169068674
Locus: 6q27
Gene Diseases
The ARID1B SMOC2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|