ARID1A-RNF31 Fusion FISH Probe
The ARID1A-RNF31 Fusion FISH Probe is used to confirm a fusion of the ARID1A and RNF31 genes. The fusion of the ARID1A and RNF31 genes has been associated with Glioblastoma Multiforme, and Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARID1A-RNF31-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-RERE | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-REOR | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-REGO | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-REGR | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-REAQ | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-ORRE | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-OROR | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-ORGO | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-GORE | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-GOOR | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-GOGO | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-GOGR | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-GRRE | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-GROR | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-GRGO | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-GRGR | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-AQRE | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-AQOR | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-AQGO | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-AQGR | 20 (40 μL) | 200 μL |
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| ARID1A-RNF31-20-AQAQ | 20 (40 μL) | 200 μL |
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ARID1A Gene Summary
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: AT-rich Interaction Domain 1A
Chromosome: CHR1: 27022521 -27108601
Locus: 1p36.11
RNF31 Gene Summary
The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. The encoded protein is the E3 ubiquitin-protein ligase component of the linear ubiquitin chain assembly complex. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
Gene Name: Ring Finger Protein 31
Chromosome: CHR14: 24616658 -24629870
Locus: 14q12
Gene Diseases
The ARID1A RNF31 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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