ARHGEF7-PKIB Fusion FISH Probe
The ARHGEF7-PKIB Fusion FISH Probe is used to confirm a fusion of the ARHGEF7 and PKIB genes. The fusion of the ARHGEF7 and PKIB genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGEF7-PKIB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGEF7-PKIB-20-AQAQ | 20 (40 μL) | 200 μL |
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PKIB Gene Summary
This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Name: CAMP-dependent Protein Kinase Inhibitor Beta
Chromosome: CHR6: 122793061 -123047518
Locus: 6q22.31
ARHGEF7 Gene Summary
This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Mar 2016]
Gene Name: Rho Guanine Nucleotide Exchange Factor 7
Chromosome: CHR13: 111767623 -111947542
Locus: 13q34
Gene Diseases
The ARHGEF7 PKIB Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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