ARHGEF7-KLF10 Fusion FISH Probe
The ARHGEF7-KLF10 Fusion FISH Probe is used to confirm a fusion of the ARHGEF7 and KLF10 genes. The fusion of the ARHGEF7 and KLF10 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGEF7-KLF10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGEF7-KLF10-20-AQAQ | 20 (40 μL) | 200 μL |
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KLF10 Gene Summary
This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Gene Name: Kruppel Like Factor 10
Chromosome: CHR8: 103661004 -103667983
Locus: 8q22.3
ARHGEF7 Gene Summary
This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Mar 2016]
Gene Name: Rho Guanine Nucleotide Exchange Factor 7
Chromosome: CHR13: 111767623 -111947542
Locus: 13q34
Gene Diseases
The ARHGEF7 KLF10 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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