ARHGEF3-RHAG Fusion FISH Probe
The ARHGEF3-RHAG Fusion FISH Probe is used to confirm a fusion of the ARHGEF3 and RHAG genes. The fusion of the ARHGEF3 and RHAG genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGEF3-RHAG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGEF3-RHAG-20-AQAQ | 20 (40 μL) | 200 μL |
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RHAG Gene Summary
The protein encoded by this gene is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides. Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN), or Rh-deficiency syndrome.[provided by RefSeq, Mar 2009]
Gene Name: Rh Associated Glycoprotein
Chromosome: CHR6: 49572889 -49604587
Locus: 6p12.3
ARHGEF3 Gene Summary
Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Rho Guanine Nucleotide Exchange Factor 3
Chromosome: CHR3: 56761445 -57113336
Locus: 3p14.3
Gene Diseases
The ARHGEF3 RHAG Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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