ARHGEF3-ACP6 Fusion FISH Probe
The ARHGEF3-ACP6 Fusion FISH Probe is used to confirm a fusion of the ARHGEF3 and ACP6 genes. The fusion of the ARHGEF3 and ACP6 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGEF3-ACP6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF3-ACP6-20-AQAQ | 20 (40 μL) | 200 μL |
|
ARHGEF3 Gene Summary
Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Rho Guanine Nucleotide Exchange Factor 3
Chromosome: CHR3: 56761445 -57113336
Locus: 3p14.3
ACP6 Gene Summary
This gene encodes a member of the histidine acid phosphatase protein family. The encoded protein hydrolyzes lysophosphatidic acid, which is involved in G protein-coupled receptor signaling, lipid raft modulation, and in balancing lipid composition within the cell. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2016]
Gene Name: Acid Phosphatase 6, Lysophosphatidic
Chromosome: CHR1: 147119167 -147142634
Locus: 1q21.2
Gene Diseases
The ARHGEF3 ACP6 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|