ARHGEF18-MAPKAP1 Fusion FISH Probe
The ARHGEF18-MAPKAP1 Fusion FISH Probe is used to confirm a fusion of the ARHGEF18 and MAPKAP1 genes. The fusion of the ARHGEF18 and MAPKAP1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGEF18-MAPKAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGEF18-MAPKAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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ARHGEF18 Gene Summary
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
Gene Name: Rho/Rac Guanine Nucleotide Exchange Factor 18
Chromosome: CHR19: 7459998 -7537371
Locus: 19p13.2
MAPKAP1 Gene Summary
This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene. [provided by RefSeq, Jul 2008]
Gene Name: Mitogen-activated Protein Kinase Associated Protein 1
Chromosome: CHR9: 128199672 -128469513
Locus: 9q33.3
Gene Diseases
The ARHGEF18 MAPKAP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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