ARHGEF18-ACACB Fusion FISH Probe
The ARHGEF18-ACACB Fusion FISH Probe is used to confirm a fusion of the ARHGEF18 and ACACB genes. The fusion of the ARHGEF18 and ACACB genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGEF18-ACACB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ARHGEF18-ACACB-20-AQAQ | 20 (40 μL) | 200 μL |
|
ACACB Gene Summary
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Acetyl-CoA Carboxylase Beta
Chromosome: CHR12: 109577201 -109706030
Locus: 12q24.11
ARHGEF18 Gene Summary
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
Gene Name: Rho/Rac Guanine Nucleotide Exchange Factor 18
Chromosome: CHR19: 7459998 -7537371
Locus: 19p13.2
Gene Diseases
The ARHGEF18 ACACB Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|