ARHGDIA-ACVRL1 Fusion FISH Probe
The ARHGDIA-ACVRL1 Fusion FISH Probe is used to confirm a fusion of the ARHGDIA and ACVRL1 genes. The fusion of the ARHGDIA and ACVRL1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGDIA-ACVRL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGDIA-ACVRL1-20-AQAQ | 20 (40 μL) | 200 μL |
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ACVRL1 Gene Summary
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008]
Gene Name: Activin A Receptor Like Type 1
Chromosome: CHR12: 52301201 -52317145
Locus: 12q13.13
ARHGDIA Gene Summary
This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: Rho GDP Dissociation Inhibitor Alpha
Chromosome: CHR17: 79825596 -79829282
Locus: 17q25.3
Gene Diseases
The ARHGDIA ACVRL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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