ARHGAP29-MID2 Fusion FISH Probe
The ARHGAP29-MID2 Fusion FISH Probe is used to confirm a fusion of the ARHGAP29 and MID2 genes. The fusion of the ARHGAP29 and MID2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGAP29-MID2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGAP29-MID2-20-AQAQ | 20 (40 μL) | 200 μL |
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ARHGAP29 Gene Summary
Rap1 is a small GTPase that, through effectors, regulates Rho GTPase signaling. These effectors- Rasip1, Radil, and the protein encoded by this gene- translocate to the cell membrane, where they form a multiprotein complex. This complex is necessary for Rap1-induced inhibition of Rho signaling. Defects in this gene may be a cause of nonsyndromic cleft lip with or without cleft palate. [provided by RefSeq, Jun 2016]
Gene Name: Rho GTPase Activating Protein 29
Chromosome: CHR1: 94634462 -94703307
Locus: 1p22.1
MID2 Gene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]
Gene Name: Midline 2
Chromosome: CHRX: 107069083 -107174867
Locus: Xq22.3
Gene Diseases
The ARHGAP29 MID2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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