ARHGAP21-PDCD11 Fusion FISH Probe
The ARHGAP21-PDCD11 Fusion FISH Probe is used to confirm a fusion of the ARHGAP21 and PDCD11 genes. The fusion of the ARHGAP21 and PDCD11 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGAP21-PDCD11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGAP21-PDCD11-20-AQAQ | 20 (40 μL) | 200 μL |
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PDCD11 Gene Summary
PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).[supplied by OMIM, Oct 2008]
Gene Name: Programmed Cell Death 11
Chromosome: CHR10: 105156411 -105206019
Locus: 10q24.33
ARHGAP21 Gene Summary
ARHGAP21 functions preferentially as a GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of CDC42 activity (Dubois et al., 2005 [PubMed 15793564]).[supplied by OMIM, Mar 2008]
Gene Name: Rho GTPase Activating Protein 21
Chromosome: CHR10: 24872537 -25012597
Locus: 10p12.3
Gene Diseases
The ARHGAP21 PDCD11 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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