ARHGAP21-ENKUR Fusion FISH Probe
The ARHGAP21-ENKUR Fusion FISH Probe is used to confirm a fusion of the ARHGAP21 and ENKUR genes. The fusion of the ARHGAP21 and ENKUR genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGAP21-ENKUR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGAP21-ENKUR-20-AQAQ | 20 (40 μL) | 200 μL |
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ARHGAP21 Gene Summary
ARHGAP21 functions preferentially as a GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of CDC42 activity (Dubois et al., 2005 [PubMed 15793564]).[supplied by OMIM, Mar 2008]
Gene Name: Rho GTPase Activating Protein 21
Chromosome: CHR10: 24872537 -25012597
Locus: 10p12.3
ENKUR Gene Summary
This gene encodes a protein that interacts with calmodulin and several transient receptor potential canonical cation channel proteins. The encoded protein may function as an adaptor to localize signal transduction machinery to calcium channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Gene Name: Enkurin, TRPC Channel Interacting Protein
Chromosome: CHR10: 25270916 -25305030
Locus: 10p12.1
Gene Diseases
The ARHGAP21 ENKUR Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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