ARHGAP18-THEMIS Fusion FISH Probe
The ARHGAP18-THEMIS Fusion FISH Probe is used to confirm a fusion of the ARHGAP18 and THEMIS genes. The fusion of the ARHGAP18 and THEMIS genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGAP18-THEMIS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGAP18-THEMIS-20-AQAQ | 20 (40 μL) | 200 μL |
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ARHGAP18 Gene Summary
ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate cell signaling (Potkin et al., 2009 [PubMed 19065146]).[supplied by OMIM, Apr 2010]
Gene Name: Rho GTPase Activating Protein 18
Chromosome: CHR6: 129898239 -130031370
Locus: 6q22.33
THEMIS Gene Summary
This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Gene Name: Thymocyte Selection Associated
Chromosome: CHR6: 128029338 -128239776
Locus: 6q22.33
Gene Diseases
The ARHGAP18 THEMIS Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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