ARHGAP15-KYNU Fusion FISH Probe
The ARHGAP15-KYNU Fusion FISH Probe is used to confirm a fusion of the ARHGAP15 and KYNU genes. The fusion of the ARHGAP15 and KYNU genes has been associated with Lung Adenocarcinoma, and Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGAP15-KYNU-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGAP15-KYNU-20-AQAQ | 20 (40 μL) | 200 μL |
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KYNU Gene Summary
Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
Gene Name: Kynureninase
Chromosome: CHR2: 143635194 -143799885
Locus: 2q22.2
ARHGAP15 Gene Summary
RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008]
Gene Name: Rho GTPase Activating Protein 15
Chromosome: CHR2: 143886898 -144525921
Locus: 2q22.2-q22.3
Gene Diseases
The ARHGAP15 KYNU Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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