ARFGEF2-CNIH2 Fusion FISH Probe
The ARFGEF2-CNIH2 Fusion FISH Probe is used to confirm a fusion of the ARFGEF2 and CNIH2 genes. The fusion of the ARFGEF2 and CNIH2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARFGEF2-CNIH2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-RERE | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-REOR | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-REGO | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-REGR | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-REAQ | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-ORRE | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-OROR | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-ORGO | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-GORE | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-GOOR | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-GOGO | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-GOGR | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-GRRE | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-GROR | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-GRGO | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-GRGR | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-AQRE | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-AQOR | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-AQGO | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-AQGR | 20 (40 μL) | 200 μL |
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| ARFGEF2-CNIH2-20-AQAQ | 20 (40 μL) | 200 μL |
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ARFGEF2 Gene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2
Chromosome: CHR20: 47538274 -47653230
Locus: 20q13.13
CNIH2 Gene Summary
The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Name: Cornichon Family AMPA Receptor Auxiliary Protein 2
Chromosome: CHR11: 66045695 -66051683
Locus: 11q13.2
Gene Diseases
The ARFGEF2 CNIH2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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