ARFGAP3-LSM10 Fusion FISH Probe
The ARFGAP3-LSM10 Fusion FISH Probe is used to confirm a fusion of the ARFGAP3 and LSM10 genes. The fusion of the ARFGAP3 and LSM10 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARFGAP3-LSM10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-RERE | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-REOR | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-REGO | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-REGR | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-REAQ | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-ORRE | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-OROR | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-ORGO | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-GORE | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-GOOR | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-GOGO | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-GOGR | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-GRRE | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-GROR | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-GRGO | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-GRGR | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-AQRE | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-AQOR | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-AQGO | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-AQGR | 20 (40 μL) | 200 μL |
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| ARFGAP3-LSM10-20-AQAQ | 20 (40 μL) | 200 μL |
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ARFGAP3 Gene Summary
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008]
Gene Name: ADP Ribosylation Factor GTPase Activating Protein 3
Chromosome: CHR22: 43192531 -43253408
Locus: 22q13.2
LSM10 Gene Summary
The LSM10, U7 Small Nuclear RNA Associated (LSM10) gene is located on chr1 :36859030-36863493 at 1p34.3.
Gene Name: LSM10, U7 Small Nuclear RNA Associated
Chromosome: CHR1: 36859030 -36863493
Locus: 1p34.3
Gene Diseases
The ARFGAP3 LSM10 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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