ARF3-WNT10B Fusion FISH Probe
The ARF3-WNT10B Fusion FISH Probe is used to confirm a fusion of the ARF3 and WNT10B genes. The fusion of the ARF3 and WNT10B genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARF3-WNT10B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-RERE | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-REOR | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-REGO | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-REGR | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-REAQ | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-ORRE | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-OROR | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-ORGO | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-GORE | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-GOOR | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-GOGO | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-GOGR | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-GRRE | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-GROR | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-GRGO | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-GRGR | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-AQRE | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-AQOR | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-AQGO | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-AQGR | 20 (40 μL) | 200 μL |
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| ARF3-WNT10B-20-AQAQ | 20 (40 μL) | 200 μL |
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ARF3 Gene Summary
ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor 3
Chromosome: CHR12: 49329991 -49351252
Locus: 12q13.12
WNT10B Gene Summary
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008]
Gene Name: Wnt Family Member 10B
Chromosome: CHR12: 49359122 -49365641
Locus: 12q13.12
Gene Diseases
The ARF3 WNT10B Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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