ARF3-CHFR Fusion FISH Probe
The ARF3-CHFR Fusion FISH Probe is used to confirm a fusion of the ARF3 and CHFR genes. The fusion of the ARF3 and CHFR genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARF3-CHFR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ARF3-CHFR-20-AQAQ | 20 (40 μL) | 200 μL |
|
ARF3 Gene Summary
ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor 3
Chromosome: CHR12: 49329991 -49351252
Locus: 12q13.12
CHFR Gene Summary
This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014]
Gene Name: Checkpoint With Forkhead And Ring Finger Domains
Chromosome: CHR12: 133416937 -133464204
Locus: 12q24.33
Gene Diseases
The ARF3 CHFR Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|