AQP3-B2M Fusion FISH Probe
The AQP3-B2M Fusion FISH Probe is used to confirm a fusion of the AQP3 and B2M genes. The fusion of the AQP3 and B2M genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AQP3-B2M-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-RERE | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-REOR | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-REGO | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-REGR | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-REAQ | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-ORRE | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-OROR | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-ORGO | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-ORAQ | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-GORE | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-GOOR | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-GOGO | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-GOGR | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-GOAQ | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-GRRE | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-GROR | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-GRGO | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-GRGR | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-GRAQ | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-AQRE | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-AQOR | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-AQGO | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-AQGR | 20 (40 μL) | 200 μL |
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| AQP3-B2M-20-AQAQ | 20 (40 μL) | 200 μL |
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AQP3 Gene Summary
This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Name: Aquaporin 3 (Gill Blood Group)
Chromosome: CHR9: 33441151 -33447631
Locus: 9p13.3
B2M Gene Summary
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]
Gene Name: Beta-2-microglobulin
Chromosome: CHR15: 45003684 -45010357
Locus: 15q21.1
Gene Diseases
The AQP3 B2M Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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