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AQP1-CFB Fusion FISH Probe

The AQP1-CFB Fusion FISH Probe is used to confirm a fusion of the AQP1 and CFB genes. The fusion of the AQP1 and CFB genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AQP1-CFB-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AQP1-CFB-20-RERE 20 (40 μL) 200 μL
AQP1-CFB-20-REOR 20 (40 μL) 200 μL
AQP1-CFB-20-REGO 20 (40 μL) 200 μL
AQP1-CFB-20-REGR 20 (40 μL) 200 μL
AQP1-CFB-20-REAQ 20 (40 μL) 200 μL
AQP1-CFB-20-ORRE 20 (40 μL) 200 μL
AQP1-CFB-20-OROR 20 (40 μL) 200 μL
AQP1-CFB-20-ORGO 20 (40 μL) 200 μL
AQP1-CFB-20-ORAQ 20 (40 μL) 200 μL
AQP1-CFB-20-GORE 20 (40 μL) 200 μL
AQP1-CFB-20-GOOR 20 (40 μL) 200 μL
AQP1-CFB-20-GOGO 20 (40 μL) 200 μL
AQP1-CFB-20-GOGR 20 (40 μL) 200 μL
AQP1-CFB-20-GOAQ 20 (40 μL) 200 μL
AQP1-CFB-20-GRRE 20 (40 μL) 200 μL
AQP1-CFB-20-GROR 20 (40 μL) 200 μL
AQP1-CFB-20-GRGO 20 (40 μL) 200 μL
AQP1-CFB-20-GRGR 20 (40 μL) 200 μL
AQP1-CFB-20-GRAQ 20 (40 μL) 200 μL
AQP1-CFB-20-AQRE 20 (40 μL) 200 μL
AQP1-CFB-20-AQOR 20 (40 μL) 200 μL
AQP1-CFB-20-AQGO 20 (40 μL) 200 μL
AQP1-CFB-20-AQGR 20 (40 μL) 200 μL
AQP1-CFB-20-AQAQ 20 (40 μL) 200 μL

AQP1 Gene Summary

This gene encodes a small integral membrane protein with six bilayer spanning domains that functions as a water channel protein. This protein permits passive transport of water along an osmotic gradient. This gene is a possible candidate for disorders involving imbalance in ocular fluid movement. [provided by RefSeq, Aug 2016]

Gene Name: Aquaporin 1 (Colton Blood Group)

Chromosome: CHR7: 30951414 -30965131

Locus: 7p14.3

CFB Gene Summary

This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008]

Gene Name: Complement Factor B

Chromosome: CHR6_dbb_hap3: 3199308 -3205449

Locus: 6p21.33

Gene Diseases

The AQP1 CFB Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.