APTX-ARL5B Fusion FISH Probe
The APTX-ARL5B Fusion FISH Probe is used to confirm a fusion of the APTX and ARL5B genes. The fusion of the APTX and ARL5B genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| APTX-ARL5B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-RERE | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-REOR | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-REGO | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-REGR | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-REAQ | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-ORRE | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-OROR | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-ORGO | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-ORAQ | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-GORE | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-GOOR | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-GOGO | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-GOGR | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-GOAQ | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-GRRE | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-GROR | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-GRGO | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-GRGR | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-GRAQ | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-AQRE | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-AQOR | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-AQGO | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-AQGR | 20 (40 μL) | 200 μL |
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| APTX-ARL5B-20-AQAQ | 20 (40 μL) | 200 μL |
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APTX Gene Summary
This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Aug 2010]
Gene Name: Aprataxin
Chromosome: CHR9: 32972603 -33001639
Locus: 9p21.1
ARL5B Gene Summary
ARL5B (ARL8) belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs; see MIM 103180). ARLs and ARFs are part of the RAS superfamily of regulatory GTPases.[supplied by OMIM, Nov 2010]
Gene Name: ADP Ribosylation Factor Like GTPase 5B
Chromosome: CHR10: 18948312 -18966940
Locus: 10p12.31
Gene Diseases
The APTX ARL5B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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