APPBP2-SETD2 Fusion FISH Probe
The APPBP2-SETD2 Fusion FISH Probe is used to confirm a fusion of the APPBP2 and SETD2 genes. The fusion of the APPBP2 and SETD2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| APPBP2-SETD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-RERE | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-REOR | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-REGO | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-REGR | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-REAQ | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-ORRE | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-OROR | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-ORGO | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-ORAQ | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-GORE | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-GOOR | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-GOGO | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-GOGR | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-GOAQ | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-GRRE | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-GROR | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-GRGO | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-GRGR | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-GRAQ | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-AQRE | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-AQOR | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-AQGO | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-AQGR | 20 (40 μL) | 200 μL |
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| APPBP2-SETD2-20-AQAQ | 20 (40 μL) | 200 μL |
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APPBP2 Gene Summary
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: Amyloid Beta Precursor Protein Binding Protein 2
Chromosome: CHR17: 58520519 -58603580
Locus: 17q23.2
SETD2 Gene Summary
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
Gene Name: SET Domain Containing 2
Chromosome: CHR3: 47057897 -47205467
Locus: 3p21.31
Gene Diseases
The APPBP2 SETD2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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