APPBP2-CA10 Fusion FISH Probe
The APPBP2-CA10 Fusion FISH Probe is used to confirm a fusion of the APPBP2 and CA10 genes. The fusion of the APPBP2 and CA10 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| APPBP2-CA10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-RERE | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-REOR | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-REGO | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-REGR | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-REAQ | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-ORRE | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-OROR | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-ORGO | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-ORAQ | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-GORE | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-GOOR | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-GOGO | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-GOGR | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-GOAQ | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-GRRE | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-GROR | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-GRGO | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-GRGR | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-GRAQ | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-AQRE | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-AQOR | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-AQGO | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-AQGR | 20 (40 μL) | 200 μL |
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| APPBP2-CA10-20-AQAQ | 20 (40 μL) | 200 μL |
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APPBP2 Gene Summary
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: Amyloid Beta Precursor Protein Binding Protein 2
Chromosome: CHR17: 58520519 -58603580
Locus: 17q23.2
CA10 Gene Summary
This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Carbonic Anhydrase 10
Chromosome: CHR17: 49707673 -50237377
Locus: 17q21.33-q22
Gene Diseases
The APPBP2 CA10 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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