APOE-SNW1 Fusion FISH Probe
The APOE-SNW1 Fusion FISH Probe is used to confirm a fusion of the APOE and SNW1 genes. The fusion of the APOE and SNW1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| APOE-SNW1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-RERE | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-REOR | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-REGO | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-REGR | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-REAQ | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-ORRE | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-OROR | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-ORGO | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-ORAQ | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-GORE | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-GOOR | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-GOGO | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-GOGR | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-GOAQ | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-GRRE | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-GROR | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-GRGO | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-GRGR | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-GRAQ | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-AQRE | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-AQOR | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-AQGO | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-AQGR | 20 (40 μL) | 200 μL |
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| APOE-SNW1-20-AQAQ | 20 (40 μL) | 200 μL |
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APOE Gene Summary
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]
Gene Name: Apolipoprotein E
Chromosome: CHR19: 45409038 -45412650
Locus: 19q13.32
SNW1 Gene Summary
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Name: SNW Domain Containing 1
Chromosome: CHR14: 78183943 -78227497
Locus: 14q24.3
Gene Diseases
The APOE SNW1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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