APOE-IQGAP2 Fusion FISH Probe
The APOE-IQGAP2 Fusion FISH Probe is used to confirm a fusion of the APOE and IQGAP2 genes. The fusion of the APOE and IQGAP2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| APOE-IQGAP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-RERE | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-REOR | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-REGO | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-REGR | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-REAQ | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-ORRE | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-OROR | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-ORGO | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-GORE | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-GOOR | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-GOGO | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-GOGR | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-GRRE | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-GROR | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-GRGO | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-GRGR | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-AQRE | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-AQOR | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-AQGO | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-AQGR | 20 (40 μL) | 200 μL |
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| APOE-IQGAP2-20-AQAQ | 20 (40 μL) | 200 μL |
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APOE Gene Summary
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]
Gene Name: Apolipoprotein E
Chromosome: CHR19: 45409038 -45412650
Locus: 19q13.32
IQGAP2 Gene Summary
This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]
Gene Name: IQ Motif Containing GTPase Activating Protein 2
Chromosome: CHR5: 75699148 -76003957
Locus: 5q13.3
Gene Diseases
The APOE IQGAP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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