APBB2-DMD Fusion FISH Probe
The APBB2-DMD Fusion FISH Probe is used to confirm a fusion of the APBB2 and DMD genes. The fusion of the APBB2 and DMD genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| APBB2-DMD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-RERE | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-REOR | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-REGO | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-REGR | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-REAQ | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-ORRE | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-OROR | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-ORGO | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-ORAQ | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-GORE | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-GOOR | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-GOGO | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-GOGR | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-GOAQ | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-GRRE | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-GROR | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-GRGO | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-GRGR | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-GRAQ | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-AQRE | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-AQOR | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-AQGO | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-AQGR | 20 (40 μL) | 200 μL |
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| APBB2-DMD-20-AQAQ | 20 (40 μL) | 200 μL |
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APBB2 Gene Summary
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: Amyloid Beta Precursor Protein Binding Family B Member 2
Chromosome: CHR4: 40812043 -41216635
Locus: 4p14-p13
DMD Gene Summary
This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
Gene Name: Dystrophin
Chromosome: CHRX: 31137344 -33357726
Locus: Xp21.2-p21.1
Gene Diseases
The APBB2 DMD Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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