APBA2-SOAT2 Fusion FISH Probe
The APBA2-SOAT2 Fusion FISH Probe is used to confirm a fusion of the APBA2 and SOAT2 genes. The fusion of the APBA2 and SOAT2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| APBA2-SOAT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-RERE | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-REOR | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-REGO | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-REGR | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-REAQ | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-ORRE | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-OROR | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-ORGO | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-GORE | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-GOOR | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-GOGO | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-GOGR | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-GRRE | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-GROR | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-GRGO | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-GRGR | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-AQRE | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-AQOR | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-AQGO | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-AQGR | 20 (40 μL) | 200 μL |
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| APBA2-SOAT2-20-AQAQ | 20 (40 μL) | 200 μL |
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APBA2 Gene Summary
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2017]
Gene Name: Amyloid Beta Precursor Protein Binding Family A Member 2
Chromosome: CHR15: 29213839 -29410516
Locus: 15q13.1
SOAT2 Gene Summary
Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
Gene Name: Sterol O-acyltransferase 2
Chromosome: CHR12: 53497273 -53518323
Locus: 12q13.13
Gene Diseases
The APBA2 SOAT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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