AP3D1-PLEKHF1 Fusion FISH Probe
The AP3D1-PLEKHF1 Fusion FISH Probe is used to confirm a fusion of the AP3D1 and PLEKHF1 genes. The fusion of the AP3D1 and PLEKHF1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AP3D1-PLEKHF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-RERE | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-REOR | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-REGO | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-REGR | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-REAQ | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-ORRE | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-OROR | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-ORGO | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-GORE | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-GOOR | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-GOGO | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-GOGR | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-GRRE | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-GROR | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-GRGO | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-GRGR | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-AQRE | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-AQOR | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-AQGO | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-AQGR | 20 (40 μL) | 200 μL |
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| AP3D1-PLEKHF1-20-AQAQ | 20 (40 μL) | 200 μL |
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AP3D1 Gene Summary
The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Defects in this gene are a cause of a new type of Hermansky-Pudlak syndrome. [provided by RefSeq, Feb 2017]
Gene Name: Adaptor Related Protein Complex 3 Delta 1 Subunit
Chromosome: CHR19: 2100992 -2151556
Locus: 19p13.3
PLEKHF1 Gene Summary
The Pleckstrin Homology And FYVE Domain Containing 1 (PLEKHF1) gene is located on chr19 :30156326-30166383 at 19q12.
Gene Name: Pleckstrin Homology And FYVE Domain Containing 1
Chromosome: CHR19: 30156326 -30166383
Locus: 19q12
Gene Diseases
The AP3D1 PLEKHF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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