AP2A2-TALDO1 Fusion FISH Probe
The AP2A2-TALDO1 Fusion FISH Probe is used to confirm a fusion of the AP2A2 and TALDO1 genes. The fusion of the AP2A2 and TALDO1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AP2A2-TALDO1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-RERE | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-REOR | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-REGO | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-REGR | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-REAQ | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-ORRE | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-OROR | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-ORGO | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-ORAQ | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-GORE | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-GOOR | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-GOGO | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-GOGR | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-GOAQ | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-GRRE | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-GROR | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-GRGO | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-GRGR | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-GRAQ | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-AQRE | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-AQOR | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-AQGO | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-AQGR | 20 (40 μL) | 200 μL |
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| AP2A2-TALDO1-20-AQAQ | 20 (40 μL) | 200 μL |
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AP2A2 Gene Summary
The protein encoded by this gene is a subunit of the AP-2 adaptor protein complex, which is involved in linking lipid and protein membrane components with the clathrin lattice. This interaction supports the formation of clathrin-coated vesicles, and the encoded subunit aids in the process by binding polyphosphoinositide-containing lipids in the cell membrane. [provided by RefSeq, Nov 2016]
Gene Name: Adaptor Related Protein Complex 2 Alpha 2 Subunit
Chromosome: CHR11: 925808 -1012245
Locus: 11p15.5
TALDO1 Gene Summary
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]
Gene Name: Transaldolase 1
Chromosome: CHR11: 747431 -765024
Locus: 11p15.5
Gene Diseases
The AP2A2 TALDO1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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