AP2A2-NLRC5 Fusion FISH Probe
The AP2A2-NLRC5 Fusion FISH Probe is used to confirm a fusion of the AP2A2 and NLRC5 genes. The fusion of the AP2A2 and NLRC5 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AP2A2-NLRC5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-RERE | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-REOR | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-REGO | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-REGR | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-REAQ | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-ORRE | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-OROR | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-ORGO | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-ORAQ | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-GORE | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-GOOR | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-GOGO | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-GOGR | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-GOAQ | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-GRRE | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-GROR | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-GRGO | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-GRGR | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-GRAQ | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-AQRE | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-AQOR | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-AQGO | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-AQGR | 20 (40 μL) | 200 μL |
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| AP2A2-NLRC5-20-AQAQ | 20 (40 μL) | 200 μL |
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AP2A2 Gene Summary
The protein encoded by this gene is a subunit of the AP-2 adaptor protein complex, which is involved in linking lipid and protein membrane components with the clathrin lattice. This interaction supports the formation of clathrin-coated vesicles, and the encoded subunit aids in the process by binding polyphosphoinositide-containing lipids in the cell membrane. [provided by RefSeq, Nov 2016]
Gene Name: Adaptor Related Protein Complex 2 Alpha 2 Subunit
Chromosome: CHR11: 925808 -1012245
Locus: 11p15.5
NLRC5 Gene Summary
This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. [provided by RefSeq, Oct 2011]
Gene Name: NLR Family CARD Domain Containing 5
Chromosome: CHR16: 57023409 -57117436
Locus: 16q13
Gene Diseases
The AP2A2 NLRC5 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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