AP1S1-PTOV1 Fusion FISH Probe
The AP1S1-PTOV1 Fusion FISH Probe is used to confirm a fusion of the AP1S1 and PTOV1 genes. The fusion of the AP1S1 and PTOV1 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AP1S1-PTOV1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-RERE | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-REOR | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-REGO | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-REGR | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-REAQ | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-ORRE | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-OROR | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-ORGO | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-ORAQ | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-GORE | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-GOOR | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-GOGO | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-GOGR | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-GOAQ | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-GRRE | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-GROR | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-GRGO | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-GRGR | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-GRAQ | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-AQRE | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-AQOR | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-AQGO | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-AQGR | 20 (40 μL) | 200 μL |
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| AP1S1-PTOV1-20-AQAQ | 20 (40 μL) | 200 μL |
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AP1S1 Gene Summary
The protein encoded by this gene is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle. [provided by RefSeq, Jul 2008]
Gene Name: Adaptor Related Protein Complex 1 Sigma 1 Subunit
Chromosome: CHR7: 100797685 -100804557
Locus: 7q22.1
PTOV1 Gene Summary
This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Gene Name: Prostate Tumor Overexpressed 1
Chromosome: CHR19: 50354415 -50363999
Locus: 19q13.33
Gene Diseases
The AP1S1 PTOV1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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