AP1M1-CYP4F11 Fusion FISH Probe
The AP1M1-CYP4F11 Fusion FISH Probe is used to confirm a fusion of the AP1M1 and CYP4F11 genes. The fusion of the AP1M1 and CYP4F11 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AP1M1-CYP4F11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-RERE | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-REOR | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-REGO | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-REGR | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-OROR | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-GORE | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-GROR | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| AP1M1-CYP4F11-20-AQAQ | 20 (40 μL) | 200 μL |
|
AP1M1 Gene Summary
The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Adaptor Related Protein Complex 1 Mu 1 Subunit
Chromosome: CHR19: 16308664 -16346156
Locus: 19p13.11
CYP4F11 Gene Summary
This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Cytochrome P450 Family 4 Subfamily F Member 11
Chromosome: CHR19: 16023179 -16045676
Locus: 19p13.12
Gene Diseases
The AP1M1 CYP4F11 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|