AP1G1-PMFBP1 Fusion FISH Probe
The AP1G1-PMFBP1 Fusion FISH Probe is used to confirm a fusion of the AP1G1 and PMFBP1 genes. The fusion of the AP1G1 and PMFBP1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AP1G1-PMFBP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-RERE | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-REOR | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-REGO | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-REGR | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-REAQ | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-ORRE | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-OROR | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-ORGO | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-GORE | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-GOOR | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-GOGO | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-GOGR | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-GRRE | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-GROR | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-GRGO | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-GRGR | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-AQRE | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-AQOR | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-AQGO | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-AQGR | 20 (40 μL) | 200 μL |
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| AP1G1-PMFBP1-20-AQAQ | 20 (40 μL) | 200 μL |
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AP1G1 Gene Summary
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Adaptor Related Protein Complex 1 Gamma 1 Subunit
Chromosome: CHR16: 71762904 -71842976
Locus: 16q22.2
PMFBP1 Gene Summary
The Polyamine Modulated Factor 1 Binding Protein 1 (PMFBP1) gene is located on chr16 :72152995-72206349 at 16q22.2.
Gene Name: Polyamine Modulated Factor 1 Binding Protein 1
Chromosome: CHR16: 72152995 -72206349
Locus: 16q22.2
Gene Diseases
The AP1G1 PMFBP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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