AP1B1-SGSM3 Fusion FISH Probe
The AP1B1-SGSM3 Fusion FISH Probe is used to confirm a fusion of the AP1B1 and SGSM3 genes. The fusion of the AP1B1 and SGSM3 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AP1B1-SGSM3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-RERE | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-REOR | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-REGO | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-REGR | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-REAQ | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-ORRE | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-OROR | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-ORGO | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-ORAQ | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-GORE | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-GOOR | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-GOGO | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-GOGR | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-GOAQ | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-GRRE | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-GROR | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-GRGO | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-GRGR | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-GRAQ | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-AQRE | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-AQOR | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-AQGO | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-AQGR | 20 (40 μL) | 200 μL |
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| AP1B1-SGSM3-20-AQAQ | 20 (40 μL) | 200 μL |
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AP1B1 Gene Summary
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: Adaptor Related Protein Complex 1 Beta 1 Subunit
Chromosome: CHR22: 29723668 -29784572
Locus: 22q12.2
SGSM3 Gene Summary
The Small G Protein Signaling Modulator 3 (SGSM3) gene is located on chr22 :40766594-40806293 at 22q13.1.
Gene Name: Small G Protein Signaling Modulator 3
Chromosome: CHR22: 40766594 -40806293
Locus: 22q13.1
Gene Diseases
The AP1B1 SGSM3 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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