AP1B1-NIPSNAP1 Fusion FISH Probe
The AP1B1-NIPSNAP1 Fusion FISH Probe is used to confirm a fusion of the AP1B1 and NIPSNAP1 genes. The fusion of the AP1B1 and NIPSNAP1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AP1B1-NIPSNAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-RERE | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-REOR | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-REGO | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-REGR | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-OROR | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-GORE | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-GROR | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| AP1B1-NIPSNAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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AP1B1 Gene Summary
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: Adaptor Related Protein Complex 1 Beta 1 Subunit
Chromosome: CHR22: 29723668 -29784572
Locus: 22q12.2
NIPSNAP1 Gene Summary
This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Gene Name: Nipsnap Homolog 1
Chromosome: CHR22: 29950797 -29977326
Locus: 22q12.2
Gene Diseases
The AP1B1 NIPSNAP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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