ANXA7-LGALS12 Fusion FISH Probe
The ANXA7-LGALS12 Fusion FISH Probe is used to confirm a fusion of the ANXA7 and LGALS12 genes. The fusion of the ANXA7 and LGALS12 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANXA7-LGALS12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ANXA7-LGALS12-20-AQAQ | 20 (40 μL) | 200 μL |
|
ANXA7 Gene Summary
Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq, Jul 2008]
Gene Name: Annexin A7
Chromosome: CHR10: 75135188 -75173841
Locus: 10q22.2
LGALS12 Gene Summary
This gene encodes a member of the galectin superfamily, a group of beta-galactoside-binding proteins with conserved carbohydrate recognition domains. The related mouse protein is a primary regulator of the early stages of adipose tissue development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, May 2010]
Gene Name: Galectin 12
Chromosome: CHR11: 63273523 -63284246
Locus: 11q12.3
Gene Diseases
The ANXA7 LGALS12 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|