ANXA1-TLN1 Fusion FISH Probe
The ANXA1-TLN1 Fusion FISH Probe is used to confirm a fusion of the ANXA1 and TLN1 genes. The fusion of the ANXA1 and TLN1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANXA1-TLN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-RERE | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-REOR | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-REGO | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-REGR | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-REAQ | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-ORRE | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-OROR | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-ORGO | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-GORE | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-GOOR | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-GOGO | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-GOGR | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-GRRE | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-GROR | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-GRGO | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-GRGR | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-AQRE | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-AQOR | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-AQGO | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-AQGR | 20 (40 μL) | 200 μL |
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| ANXA1-TLN1-20-AQAQ | 20 (40 μL) | 200 μL |
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ANXA1 Gene Summary
This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]
Gene Name: Annexin A1
Chromosome: CHR9: 75766780 -75785307
Locus: 9q21.13
TLN1 Gene Summary
This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009]
Gene Name: Talin 1
Chromosome: CHR9: 35697333 -35732392
Locus: 9p13.3
Gene Diseases
The ANXA1 TLN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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