ANO6-EDA Fusion FISH Probe
The ANO6-EDA Fusion FISH Probe is used to confirm a fusion of the ANO6 and EDA genes. The fusion of the ANO6 and EDA genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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ANO6-EDA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-RERE | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-REOR | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-REGO | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-REGR | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-REAQ | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-ORRE | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-OROR | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-ORGO | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-ORAQ | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-GORE | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-GOOR | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-GOGO | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-GOGR | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-GOAQ | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-GRRE | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-GROR | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-GRGO | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-GRGR | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-GRAQ | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-AQRE | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-AQOR | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-AQGO | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-AQGR | 20 (40 μL) | 200 μL | ||
ANO6-EDA-20-AQAQ | 20 (40 μL) | 200 μL |
EDA Gene Summary
The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Ectodysplasin A
Chromosome: CHRX: 68835910 -69259321
Locus: Xq13.1
ANO6 Gene Summary
This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
Gene Name: Anoctamin 6
Chromosome: CHR12: 45609769 -45834187
Locus: 12q12
Gene Diseases
The ANO6 EDA Fusion has been associated with the following diseases:
Disease Name |
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Sarcoma |
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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