ANLN-POU6F2 Fusion FISH Probe
The ANLN-POU6F2 Fusion FISH Probe is used to confirm a fusion of the ANLN and POU6F2 genes. The fusion of the ANLN and POU6F2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANLN-POU6F2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-RERE | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-REOR | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-REGO | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-REGR | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-REAQ | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-ORRE | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-OROR | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-ORGO | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-GORE | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-GOOR | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-GOGO | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-GOGR | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-GRRE | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-GROR | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-GRGO | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-GRGR | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-AQRE | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-AQOR | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-AQGO | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-AQGR | 20 (40 μL) | 200 μL |
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| ANLN-POU6F2-20-AQAQ | 20 (40 μL) | 200 μL |
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POU6F2 Gene Summary
This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
Gene Name: POU Class 6 Homeobox 2
Chromosome: CHR7: 39017608 -39504390
Locus: 7p14.1
ANLN Gene Summary
This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Gene Name: Anillin Actin Binding Protein
Chromosome: CHR7: 36429431 -36493400
Locus: 7p14.2
Gene Diseases
The ANLN POU6F2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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